The recipe in whole cc quantities is: 9 cc BSS Plus 3 cc 4% preservative-free lidocaine and 4 cc 1:1000 preservative-free, bisulfite free epinephrine. Plain BSS may be safely substituted for the BSS Plus. This ends up as buffered 0.75% lidocaine and 1:4000 epinephrine.

LET solution consists of lidocaine HCl USP 4%, epinephrine bitartrate USP 180 mg, and tetracaine HCl USP 500 mg, with sodium metabisulfite 75 mg in sterile water for irrigation USP to 100 mL. It was described as a replacement for the problematic, traditional, cocaine-containing TAC solution by Schilling et al in 1995 (Schilling CG, Bank DE Buffered lidocaine hydrochloride solution with and without RESULTS: All buffered lidocaine solutions containing epinephrine (1:100 000) retained at least 93.3% of the original concentration of epinephrine and 97.5% of the lidocaine concentration for 7 days when stored at 5°C with protection from light. In contrast, the epinephrine-free solutions retained at least 94.7% of the initial concentration of Clinical Outcomes of Buffered vs. Non-Buffered Lidocaine Dec 03, 2015 Addition of Sodium Bicarbonate to Lidocaine Decreases the

A standard recipe for buffering lidocaine consists of adding 1 mL of 8.4% sodium bicar- bonate (1 mEq per 1 mL) to 10 mL of 1% lidocaine.~-3 This 10:1 lidocaine to bicarbonate ratio will change the mildly acidic pH of lidocaine toward a more physiological range without apparent precipitation or denatur- ation of the compound.1'2 Similarly

buffered lidocaine | IV-Therapy.net

Clindamycin for Intraincisional Antibiotic Prophylaxis in

RESULTS: All buffered lidocaine solutions containing epinephrine (1:100 000) retained at least 93.3% of the original concentration of epinephrine and 97.5% of the lidocaine concentration for 7 days when stored at 5°C with protection from light. In contrast, the epinephrine-free solutions retained at least 94.7% of the initial concentration of Clinical Outcomes of Buffered vs. Non-Buffered Lidocaine Dec 03, 2015